OncoCore™ DNA+RNA
Created for fast access to actionable precision oncology, OncoCore™ is an advanced 35-gene NGS panel that uses targeted amplicon sequencing to analyze both DNA and RNA, detecting all clinically significant single nucleotide variants (SNVs), insertions and deletions (InDels), gene fusions, and microsatellite instability (MSI). This panel also pinpoints genotypes associated with resistance to common chemotherapies.

OncoCore™ incorporates microfluidic devices to achieve full automation and provides results within a rapid
3-4 day turnaround. This swift processing provides clinicians with essential, timely data to inform immunotherapy treatment decisions for their patients.
Fast, Actionable, 35 Gene Panel
  • Results within 3-4 days
  • Provides coverage of cancer-relevant biomarkers cross DNA and RNA in a single assay
  • Broad and deep sequencing coverage accurately detects mutations, rare fusions, and transcript variants
Clinical Utility
  • Comprehensive detection of actionable mutations, insertions, deletions, and gene fusions is critical for treatment decisions
  • Provides a complete solution by identifying all actionable genes relevant to FDA-approved therapies
  • Versatile testing applicable to all major types of solid tumors, enhancing diagnostic precision
Automated process
FFPE block
Extraction
of DNA and RNA
Library construction
Sequencing
Day 1
Day 2
Day 3
Interrogates 551 SNVs/InDels,
552 Fusions, MSI
Delivers high accuracy with 100% sensitivity and 100% specificity*
* if MAF level > 1.0%
Covers targeted gene mutations for NSCLC, Melanoma, Cholangiocarcinoma, Colorectal, GIST, Urothelial carcinoma and Bladder carcinoma
Highlights results in an easy-to-interpret report featuring mutations associated with FDA-approved treatments and clinical trial options
Actionable markers
Non-small cell lung cancer (NSCLC)
ALK, BRAF, EGFR, ERBB2(HER2), KRAS, MET, NTRK1, NTRK2, NTRK3, RET, ROS1
Cholangiocarcinoma
BRAF, FGFR2, IDH1, NRG1, NTRK1, NTRK2, NTRK3, RET
Gastrointestinal stromal tumor (GIST)
KIT, NTRK1, NTRK2, NTRK3, PDGFRA
Colorectal Cancer (CRC)
BRAF, KRAS, NRAS, NTRK1, NTRK2, NTRK3, RET
Urothelial carcinoma & Bladder carcinoma
FGFR2, FGFR3, NTRK1, NTRK2, NTRK3
Melanoma
ALK, BRAF , EGFR, ERBB2(HER2), KRAS, MET, NTRK1, NTRK2, NTRK3, RET, ROS

Gene list

Genes associated with targeted therapy, prognosis, and drug resistance (30 Genes)

Fusion Variants (15 Genes)

Chemotherapy related genes* (4 Genes)

*Chemotherapy results may vary based on the genotype of each individual gene

Drugs recommended by NCCN

Non-small cell lung cancer (NSCLC)

Colorectal cancer (CRC)

For information on additional malignancies recommended by the NCCN, please contact us directly.

Begin your journey- our team is ready to get you started.